Discriminant value of %microcytic cells/%hypochromic cells ratio in the differential diagnosis of microcytic anemia

Multivariable Discriminant Analysis for the Differential Diagnosis of Microcytic Anemia

Introduction. Iron deficiency anemia and thalassemia are the most common causes of microcytic anemia. Powerful statistical computer programming enables sensitive discriminant analyses to aid in the diagnosis. We aimed at investigating the performance of the multiple discriminant analysis (MDA) to the differential diagnosis of microcytic anemia. Methods. The training group was composed of 200 β ...

Differential Diagnosis of Microcytic Anemia, Thalassemia or Iron Deficiency Anemia: A Diagnostic Test Accuracy Meta-Analysis

We evaluated the most common indices to compare their sensitivity and specificity to introduce the most sensitive and specific index. We systematically searched five international indexing databases up to Dec 2018. For each index, we measured the diagnostic odds ratio (DOR), as well as summary ROC (SROC) curve which was used to compare the performance of each index. Deeks̕ tests of all discrimin...

Microcytic anemia.

Microcytic Anemia Anemia is the most common hematologic abnormality that pediatricians encounter. The differential diagnosis for anemia in children includes congenital, acquired, benign, malignant, common, and extraordinarily rare disorders. Thankfully, most conditions cause consistent changes in the mean cell volume (MCV) of red blood cells (RBCs) and can be grouped by using this parameter. In...

A case of microcytic anemia.

A 15-month-old male infant was admitted because of anemia lasting for a few months and delayed weight gain. There was no family history of anemia. At admission, the patient was pale but showed no other pathological findings. Hematological data were: Hb 8.6 g/dL, red cell count 4.8631012/L, Hct 28%, MCV 57.6 fL, MCH 17.7 pg, MCHC 30.7 g/dL, reticulocytes 1943109/L, white cell count 18.93109/L wi...

Microcytic Anemias: Sideroblastic Anemia — Causes and Treatment